As the dietary supplements industry is registering steady and rapid growth, consumers are demanding quality supplements. Consumer perception of the quality of oral solid dosage forms is changing. Good quality is associated with the ability to disintegrate and dissolve. Performance characteristics of oral solid dosage forms in public standards will address the in vitro dissolution requirements, which will be presented as they relate to multivitamin-mineral combination products. The commonly accepted definition of bioavailability is the proportion of the nutrient digested, absorbed, and metabolized through normal pathways.

Consequently, it is not enough to know how much of a nutrient is present in a dietary supplement; the more critical issue is how much of that present is bioavailable. A common belief regarding the bioavailability of dietary supplements is that they have to be in solution to be absorbed in the body. Aloe also offers ingredients and premixes targeted at skin nourishment, other aging-related concerns, and overall well-being. Mix aloe vera carotenoids, biotin, and vitamin E to deliver antioxidant protection from the sun’s rays and help slow the signs of aging; It also helps dry skin moisturize, aims to improve skin hydration and elasticity. Aloe Vera is your ingredient solution for maintaining and restoring skin health and offers nutritional ingredients that work to protect, repair, or hydrate the skin from within.

Biological activities of Aloe Vera leaf gel It has been claimed that the polysaccharides in Aloe Vera gel have therapeutic properties such as immunostimulation, anti-inflammatory effects, wound healing, promotion of radiation damage repair, anti-bacterial, anti-viral, anti-fungal, anti-diabetic, and anti-neoplastic activities, stimulation of hematopoiesis and antioxidant effects. Clinical investigations suggest that Aloe Vera Gel preparations accelerate wound healing. In vivo studies have demonstrated that Aloe Vera Gel promotes wound healing by directly stimulating macrophages and fibroblasts’ activity. Fibroblast activation by Aloe Vera Gel has been reported to increase collagen and proteoglycan synthesis, thereby promoting tissue repair. Some of the active principles appear to be polysaccharides composed of several monosaccharides, predominantly mannose. It has been suggested that mannose 6-phosphate, the principal sugar component of Aloe Vera Gel, may be partly responsible for the gel’s wound healing properties. Mannose 6-phosphate can bind to the growth factor receptors on the fibroblasts’ surface and enhance their activity.

Studies also have shown that aloe-based supplements can enhance the bioavailability of vitamins C, E, and B12; human clinical studies also have shown that aloe supplements can be beneficial for immune health, oxidative stress, interior beauty, and skin health.

Oral treatments with Aloe vera were found to positively influence the synthesis of glycosaminoglycans, thereby benefitting wound healing. Still, other studies have been done specifically showing Aloe vera can increase the granulation tissue’s collagen content, the fibrous tissue involved in wound healing. While more studies are needed to explore Aloe vera’s ingestible benefits further, there is a clear indication that Aloe vera as a supplement will help the skin look better.