Mechanism of actions of ALOE VERA in Personal Care
Healing properties: Glucomannan, a mannose-rich
polysaccharide, and gibberellin, a growth hormone,
interacts with growth factor receptors on the fibroblast,
thereby stimulating its activity and proliferation,
which in turn significantly increases collagen synthesis
after topical and oral Aloe Vera.
Aloe Vera gel not only increased collagen content of
the wound but also changed collagen composition
(more type III) and increased the degree of collagen
cross linking. Due to this, it accelerated wound contraction
and increased the breaking strength of resulting
scar tissue. An increased synthesis of hyaluronic
acid and dermatan sulfate in the granulation tissue of
a healing wound following oral or topical treatment
has been reported
Effects on skin exposure to UV and gamma radiation:
Aloe Vera gel has been reported to have a protective
effect against radiation damage to the skin, Exact role
is not known, but following the administration of Aloe
Vera gel, an antioxidant protein, metallothionein, is
generated in the skin, which scavenges hydroxyl radicals
and prevents suppression of superoxide dismutase
and glutathione peroxidase in the skin. It
reduces the production and release of skin keratinocyte-
derived immunosuppressive cytokines such as
interleukin-10 (IL-10) and hence prevents UV-induced
suppression of delayed type hypersensitivity.
Anti-inflammatory action: Aloe Vera inhibits the
cyclooxygenase pathway and reduces prostaglandin
E2 production from arachidonic acid. Recently, the
novel anti-inflammatory compound called C-glucosyl
chromone was isolated from gel extracts.
Moisturizing effect: Mucopolysaccharides help in
binding moisture into the skin. Aloe stimulates fibroblast
which produces the collagen and elastin fibers
making the skin more elastic and less wrinkled. It also
has cohesive effects on the superficial flaking epidermal
cells by sticking them together, which softens the
skin. The amino acids also soften hardened skin cells
and zinc acts as an astringent to tighten pores. Its
moisturizing effects has also been studied in treatment
of dry skin associated with occupational exposure
where Aloe Vera gel gloves improved the skin
integrity, decreases appearance of fine wrinkle and
Antiseptic effect: Aloe Vera contains 6 antiseptic
agents: Lupeol, salicylic acid, urea nitrogen, cinnamonic
acid, phenols and sulfur. They all have inhibitory
action on fungi, bacteria and viruses.
It treats sunburn. Aloe Vera helps with sunburn
through its powerful healing activity at the epithelial
level of the skin, a layer of cells that cover the body. It
acts as a protective layer on the skin and helps replenish
its moisture. Because of its nutritional qualities
and antioxidant properties, the skin heals quicker.
It acts as a moisturizer. Aloe moisturizes the skin without giving it a greasy feel, so it`s perfect for anyone with an oily
skin complexion. For women who use mineral-based make-up, Aloe Vera acts as a moisturizer and is great for the face
prior to the application to prevents skin drying. For men: Aloe Vera gel can be used as an aftershave treatment as its
healing properties can treat small cuts caused by shaving.
It treats body acne. Aloe Vera gel contains two hormones: Auxin and Gibberellins. These two hormones provide
wound healing and anti-inflammatory properties that reduce skin inflammation. Giberellin in Aloe Vera acts as a
growth hormone stimulating the growth of new cells. It allows the skin to heal quickly and naturally with minimal scarring.
Aloe is soothing and can reduce skin inflammations, blistering and itchiness, while helping the skin to heal more rapidly.
Additionally, in Ayurvedic medicine, Aloe is used to effectively heal chronic skin problems, such as psoriasis, acne
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It fights aging. As we age, everyone begins to worry about the appearance of fine lines and the loss of elasticity in their
skin. Aloe leaves contain a plethora of antioxidants including, beta carotene, vitamin C and E that can help improve the
skin's natural firmness and keep the skin hydrated.
It lessens the visibility of stretch marks. The skin is like one big piece of elastic that’ll expand and contract as needed to
accommodate growth. But if the skin stretches too far, too fast (due to pregnancy, rapid weight gain or loss) the elasticity
of the skin can be damaged. That’s what leaves those unsightly stretch marks. These marks appear due to minor
tears in the layers of the skin caused by sudden and excessive stretching. Aloe Vera gel can help hide these stretch
marks by healing these wounds.